YOUTH PROTOCOL
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Skin Protocol — AM, PM, SPF bottles on travertine
Available now · 3 components

Skin Protocol.

Visible improvements in 6–12 weeks

The Rx skincare protocol Hims can't prescribe. A compounded night treatment, a peptide support serum, and daily photoprotection — engineered to work as one system. This is where your longevity stack begins.

Full Skin Protocol
$99/month
PM + AM + SPF · ~60-day supply
Solo options
From $21/mo
Build piece by piece
Prescribed by US-licensed clinicians
Compounded at a 503A licensed pharmacy
$0 if your clinician doesn't approve
Build your Skin Protocol

Three steps.
One system.

Treatment · Rx

PM Protocol

Tretinoin · Azelaic · Niacinamide · GHK-Cu

Compounded Rx night treatment. The workhorse — drives visible aging reversal.

Learn more →
Support · OTC

AM Protocol

Matrixyl 3000 · Argireline · GHK-Cu

Peptide serum. Supports collagen, softens PM Protocol irritation.

Learn more →
Protection · OTC

SPF Protocol

SPF 50 · PA++++ · Broad Spectrum

Essential with PM Protocol. Tretinoin makes skin sun-sensitive — SPF protects what the Rx layer builds.

Learn more →
Your Skin Protocol
3 of 3 active
PM · AM · SPF
Total
$99/mo
Activate protocol
Clinical formulations
Rx-grade, research-backed
Systemic approach
Treatment + support + protection
Daily rituals
One step. Built to stick.
Visible results
Measured at 12 weeks
Projected outcome

Drag to see 12 weeks on protocol.

Based on median clinical response. Individual results vary.

Before protocol After 12 weeks on protocol
Before · Week 0
Week 12
Week 0Week 12
Questions

Answered.

Can I order just one component?+

Yes — each is available solo. But the three compound: PM drives change, AM keeps it tolerable, SPF preserves the outcome. Removing any one reduces the others' effectiveness.

Do I need all three to start?+

PM + SPF is the non-negotiable baseline. Tretinoin without daily SPF accelerates damage instead of reversing it. AM is strongly recommended but can be added later.

How long until I see results?+

Most users see smoother texture and tone within 8–12 weeks. Meaningful change in fine lines and photoaging compounds over 6–12 months of consistent use.

What if my skin reacts badly?+

Message your clinician. Strength can be adjusted — 0.05% tretinoin can step down to 0.025% within 24 hours. We don't let irritation cause you to quit.

The math

Same Rx.
1/3 the cost.

Dermatologist
$300+ / visit
  • 6–12 week wait for appointment
  • One 15-minute consult
  • Rx handed off to pharmacy
  • You figure out routine alone
  • $180/mo for 3 separate products
Drugstore / DIY
$60–140 / mo
  • No prescription compounds
  • Retinol ≈ 20× weaker than Rx tretinoin
  • No clinical oversight
  • 10+ products to manage
  • Marginal results at best
Most men choose
Youth Protocol
$99 / mo
  • Approved in 24–48 hrs online
  • US-licensed clinician, full review
  • Compound shipped from US pharmacy
  • AM/PM protocol, built to execute
  • Message your clinician anytime
Activate protocol

Toggle on the foundation.
Start your intake.

Two minutes. Clinician reviews in 24 hours. You pay nothing until approved.

Peer-reviewed evidence

The clinical data.

We read the studies so you don't have to. Here's the evidence behind Skin Protocol.

1.Landmark 24-week double-blind trial establishing tretinoin 0.05% as the gold standard for photoaging reversal.
J Am Acad Dermatol, 1988 →
2.5% niacinamide reduces wrinkles, hyperpigmentation, and improves skin elasticity in 50 subjects over 12 weeks.
Dermatol Surg, 2005 →
3.Review of GHK-Cu peptide mechanisms: stimulates collagen, elastin, and tissue repair at micromolar concentrations.
Biomed Res Int, 2015 →
4.Azelaic acid 15% shown superior to tretinoin in treating postinflammatory hyperpigmentation in men.
Cutis, 2011 →
5.Topical tretinoin + niacinamide combination: synergistic improvement in tone and texture vs. either alone.
J Cosmet Dermatol, 2019 →
6.Daily SPF 50+ reduces photoaging markers by 24% over 4.5 years in a randomized controlled trial.
Ann Intern Med, 2013 →

Selected peer-reviewed references. Full bibliography available in your patient portal.

Skin Protocol
$99/mo
Activate protocol