Reverse
visible aging.
Wake up to better skin than you went to bed with. Real Rx, daily protocol, built to stick.
Anti-aging
without botox.
“Softer forehead lines without the needles. My wife hasn’t figured out how.”
“Softer forehead lines”
I’d been resistant to botox for years. Didn’t want the maintenance, didn’t want the frozen look. A friend told me about PM Protocol — tretinoin plus a few peptides, once a night. Three months later my forehead is visibly smoother and nobody knows I’m doing anything.
“My wife stopped asking if I slept badly. Turns out it wasn’t the sleep.”
“Fix my tired eyes”
Every morning my wife would ask if I slept badly — I was getting seven hours. Turns out what she was reading as “tired” was just hollow under-eye shadows from aging. AM + PM together shifted that in ten weeks. Coworkers think I took a vacation.
“Clearer skin at 45 than I had at 25.”
“Clearer, smoother skin”
I had adult acne well into my 40s. Every OTC serum, every derm-free experiment, nothing held. What the clinician prescribed was a real tretinoin compound — not a watered-down version. My skin texture is better right now than when I was 30.
Real reviews.
Verified buyers.
“Kept telling myself I’d start a real routine. Three months in and my wife asked what I’d changed. Cheaper than my old derm and I haven’t skipped a night.”
“Tretinoin is the only thing that actually worked on my forehead lines. No appointment, no gatekeeping — clinician approved me in 18 hours and the bottle showed up that week.”
“Adult acne kept coming back at 45. PM compound + the AM serum stopped it cold. Skin texture is the smoothest it’s been since college.”
20× stronger
than anything you can buy
without a prescription.
Same Rx.
1/3 the cost.
- 6–12 week wait for appointment
- One 15-minute consult
- Rx handed off to pharmacy
- You figure out routine alone
- $180/mo for 3 separate products
- Retinol = 20× weaker than Rx tretinoin
- Cannot legally claim to reverse photoaging
- Marketing words. No clinical compounds.
- 10+ products to remember every morning
- $60–140/mo for marginal results
- Approved in 24–48 hrs online
- US-licensed clinician, full review
- Compound shipped from US pharmacy
- AM/PM protocol, built to execute
- Message your clinician anytime
“You can’t moisturize your way out of aging. You need a prescription.”
Three steps.
One minute, twice a day.
Forget 12-step routines. AM peptide serum to support, PM Rx compound to treat, SPF to protect what's healing. That's it.
Peptide serum
3 drops. Press into face after cleansing. Supports collagen, softens overnight retinoid.
Rx compound
Pea-sized amount. Once nightly. Tretinoin + niacinamide + azelaic acid + GHK-Cu. The work happens while you sleep.
SPF 50
Two-finger length. Every morning. Tretinoin makes skin 2-3× more sun-sensitive — this protects what you're building.
Prescription skincare works. Most people just can’t stick to it.
Tretinoin is the most studied topical in dermatology. Azelaic acid is gold-standard for tone. Niacinamide reduces irritation and barrier loss. GHK-Cu supports repair overnight. Protocolo compounds all four into a single nightly step — so the hard part becomes doable.
A protocol, not a product.
Four steps. Compounded over months.
Visible improvements in 6–12 weeks. After that, your skin keeps compounding while you forget it’s even happening.
Diagnose
2-minute medical intake. Skin goals, history, tolerability. Free until approved.
Prescribe
US-licensed clinician reviews and prescribes your compound. No calls. No clinic visit.
Execute daily protocol
AM and PM rituals, shipped every 60 days from a US pharmacy. Discreet packaging.
Track + optimize
Dashboard check-ins at 6 and 12 weeks. Your clinician adjusts the protocol as you go.
Activate your protocol.
Free 2-minute intake. Pay only if your clinician approves.
Activate protocol
Eight protocols.
Toggle on your stack.
Start with one. Stack as you grow. Toggle off anytime — no contract, no calls, no awkward cancellation script.
Skin Protocol
Rx anti-aging compound, peptide support, daily protection.
Hair Protocol
Finasteride, topical minoxidil, GHK-Cu for density.
Performance Protocol
Physician-managed testosterone optimization.
Peptide Protocol
CJC-Ipamorelin, BPC-157, body-comp support.
Metabolic Protocol
GLP-1 therapy, insulin sensitivity, weight.
Recovery Protocol
Sleep optimization, inflammation, tissue repair.
Cognition Protocol
Focus, memory, executive function support.
Longevity Labs
Testing + intervention. Biological age optimization.
Protocols designed
and prescribed by
licensed physicians.
Products treat symptoms. Protocols compound results. Every Protocolo prescription is reviewed and signed by a US-licensed clinician — no black-box algorithm, no offshore mill.
“Tretinoin works. The reason it fails is that 80% of men quit by week 4. A protocol is built to survive those first 4 weeks.”
“The right dose in the right vehicle, shipped on time, every time. That is 90% of what a successful Rx regimen requires.”
“Men want results without a bathroom shelf of 12 products. This is the shortest path to visible change.”
“Prescription biology, delivered consistently. That is what moves the needle — not another serum.”
Questions,
answered directly.
Is this an actual prescription?
Yes. After your intake, a US-licensed clinician reviews your profile and writes a prescription where clinically appropriate. Your compound is dispensed by a licensed US compounding pharmacy.
What's actually in the PM Protocol?
Tretinoin 0.025%, Azelaic Acid 10%, Niacinamide 4%, and GHK-Cu, compounded into a single nightly formula. Strengths may be adjusted by your clinician based on your intake and tolerability.
Will I purge or experience irritation?
Mild dryness, flaking, or initial breakouts ("purging") are common in the first 2–6 weeks as skin cell turnover accelerates. The AM Support layer is designed to reduce this. Your clinician can adjust strength if needed.
How soon will I see results?
Most users see smoother texture and tone within 8–12 weeks. Meaningful change in fine lines and photoaging typically compounds over 6–12 months of consistent nightly use.
Can I pause or cancel?
Yes. Pause or cancel anytime from your account. No retention calls, no friction. Toggle any protocol off whenever you're ready.
Is it safe during pregnancy or breastfeeding?
No. Tretinoin is contraindicated in pregnancy and breastfeeding. The intake screens for this, and your clinician will not prescribe if these apply.
Which states and countries do you serve?
Protocolo is currently available in all 50 US states. International availability is rolling out in 2026.
Start the protocol.
Activate tonight.
Two-minute intake. Free clinician review. Only pay if approved.
